Tuesday, April 11, 2017

Chemistry World: Drugs, the permanent way

Exceptions to a long-held rule against chemically bonding to biological targets are powering new cancer medicines, finds Andy Extance

https://www.chemistryworld.com/feature/covalent-inhibitor-drugs/2500494.article

Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase

Kristen A. Baltgalvis, Kelsey N. Lamb, Kent T. Symons, Chu-Chiao Wu, Melissa A. Hoffman, Aaron N. Snead, Xiaodan Song, Thomas Glaza, Shota K...