Wednesday, August 24, 2016

Angewante Chemie Review: Targeted Covalent Inhibitors for Drug Design by Thomas Baille

Targeted Covalent Inhibitors for Drug Design

The current issue of Angewante Chemie includes and extensive review on pharmaceutical inhibitors by Prof. T. A. Baillie from the Department of Medicinal Chemistry at the University of Washington.

DOI: 10.1002/anie.201601091

Exploiting human fucosyltransferase 8 allostery with a covalent inhibitor for core fucosylation suppression

Jiheng Jiang, Dongyang He, Mengyu Ke, Jinhua Qin, Guang Yang, Biao Yu, Jing Wang & Pengfei Fang  Nat Commun  (2026).  https://doi.org/10...