Monday, September 5, 2016

Cysteinome: The first comprehensive database for proteins with targetable cysteine and their covalent inhibitors

Cysteinome: The first comprehensive database for proteins with targetable cysteine and their covalent inhibitors

  • a Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116023, PR China
  • b School of Pharmacology, Dalian University of Technology, Dalian, 116023, PR China
doi: 10.1016/j.bbrc.2016.08.109

http://www.cysteinome.org/

Lysine-Targeted Covalent Inhibition of eIF4E with an Anionic Electrophile Warhead

Paramita Pal, Erika M. James, Caitlyn E. Given, Hong Yue, Rebecca J. Metivier, Jianwei Che, Eric S. Fischer, Lyn H. Jones;  ACS Chem. Biol ....