Monday, September 5, 2016

Cysteinome: The first comprehensive database for proteins with targetable cysteine and their covalent inhibitors

Cysteinome: The first comprehensive database for proteins with targetable cysteine and their covalent inhibitors

  • a Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116023, PR China
  • b School of Pharmacology, Dalian University of Technology, Dalian, 116023, PR China
doi: 10.1016/j.bbrc.2016.08.109

http://www.cysteinome.org/

Oncogenic KRAS G12C: Kinetic and Redox Characterization of Covalent Inhibition

Minh V. Huynh, Derek Parsonage, Tom E. Forshaw, Venkat R. Chirasani, G. Aaron Hobbs, Hanzhi Wu, Jingyun Lee, Cristina M. Furdui, Leslie B. P...