Monday, September 5, 2016

Cysteinome: The first comprehensive database for proteins with targetable cysteine and their covalent inhibitors

Cysteinome: The first comprehensive database for proteins with targetable cysteine and their covalent inhibitors

  • a Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116023, PR China
  • b School of Pharmacology, Dalian University of Technology, Dalian, 116023, PR China
doi: 10.1016/j.bbrc.2016.08.109

http://www.cysteinome.org/

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability

Mariantonietta D’Ambrosio, Matthew E. H. White, Efthymios S. Gavriil, Laura Bousset, Jodie Birch, Aleksandra Gruevska, Emiliano Pasquini, Ma...