Thursday, January 19, 2017

Covalent Modulators of the Vacuolar ATPase

Covalent Modulators of the Vacuolar ATPase

Ying-Chu Chen, Keriann M. Backus, Maria Merkulova, Christina Yang, Dennis Brown, Benjamin F. Cravatt, and Chao Zhang
J. Am. Chem. Soc.2017139 (2), pp 639–642

Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight

Momar Toure * ; Xin Cindy Yan; Yonghong Bai; Brian A. Sosa-Alvarado; Cen Gao; Theresa Baker; Erin Brophy; John R. Butler; Yuchen Yuan; Micha...