Thursday, January 5, 2017

What Do Reactive Fragments Actually Do in Cells?

What Do Reactive Fragments Actually Do in Cells?
Angewante Chemie
Prof. Dr. Oliver Plettenburg
DOI: 10.1002/anie.201607914
at

Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight

Momar Toure * ; Xin Cindy Yan; Yonghong Bai; Brian A. Sosa-Alvarado; Cen Gao; Theresa Baker; Erin Brophy; John R. Butler; Yuchen Yuan; Micha...