Wednesday, August 24, 2016

Angewante Chemie Review: Targeted Covalent Inhibitors for Drug Design by Thomas Baille

Targeted Covalent Inhibitors for Drug Design

The current issue of Angewante Chemie includes and extensive review on pharmaceutical inhibitors by Prof. T. A. Baillie from the Department of Medicinal Chemistry at the University of Washington.

DOI: 10.1002/anie.201601091
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Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation

Gregory B. Craven, Hang Chu, Jessica D. Sun, Jordan D. Carelli, Brittany Coyne, Hao Chen, Ying Chen, Xiaolei Ma, Subhamoy Das, Wayne Kong, A...