Tuesday, April 11, 2017

Chemistry World: Drugs, the permanent way

Exceptions to a long-held rule against chemically bonding to biological targets are powering new cancer medicines, finds Andy Extance

https://www.chemistryworld.com/feature/covalent-inhibitor-drugs/2500494.article

Ninhydrin as a covalent warhead for chemical proteomic-enabled discovery and selective engagement of reactive arginines

Andrew Ecker, Andreas Langen, Chloe Fields, José Luis Montaňo, Minh Tran, Ian Bass Seiple, Balyn W Zaro bioRxiv 2026.01.05.697388;  doi: ht...