Tuesday, September 2, 2025

Covalent chemical probes

Backus, K.M., Wilson, A.J. 

Commun Chem 8, 266 (2025). 

https://doi.org/10.1038/s42004-025-01652-6


A Tandem Bioorthogonal Retro-Cope and Cope Elimination for the Activation of Covalent Inhibitors with an Acrylamide or Vinylsulfonamide Warhead in Live Cells

Yan Huang, Miao Liu, Dongguang Fan, Fan Xu, Fushuang Xiang, Qingqiang Min, and Xingyue Ji Journal of the American Chemical Society 2026 DOI:...