Tuesday, September 2, 2025

Covalent chemical probes

Backus, K.M., Wilson, A.J. 

Commun Chem 8, 266 (2025). 

https://doi.org/10.1038/s42004-025-01652-6


A Global Ligandability Map of Tryptoline Butynamide Stereoprobes Identifies Covalent Inhibitors of the Actin Maturation Protease ACTMAP

Yijun Xiong, Christopher J. Reinhardt, Tracey Nguyen, Melissa A. Hoffman, Gabriel M. Simon, Bruno Melillo, Benjamin F. Cravatt bioRxiv , 202...