Thursday, January 5, 2017

What Do Reactive Fragments Actually Do in Cells?

What Do Reactive Fragments Actually Do in Cells?
Angewante Chemie
Prof. Dr. Oliver Plettenburg
DOI: 10.1002/anie.201607914

Discovery and Characterization of Divarasib (GDC-6036), a Potent Covalent Inhibitor of KRAS G12C

Nicholas F. Endres, Steven Do, Rana Mroue, Jack A. Terrett, Matt Saabye, Angela Oh, Thomas Hunsaker, Emily Chan, John C. Tran, Lan K. Nguyen...