Thursday, January 5, 2017

What Do Reactive Fragments Actually Do in Cells?

What Do Reactive Fragments Actually Do in Cells?
Angewante Chemie
Prof. Dr. Oliver Plettenburg
DOI: 10.1002/anie.201607914

A covalent inhibitor targeting Cys-349 of LIMK1 confers selectivity over LIMK2

Jon B. Patteson,  Ioannis Manolaridis, Mee Ra Hong,  Jennifer M. Johnston, Samaneh Mesbahi-Vasey,  Michael C. Gregory ,Daniel V. Iwamoto Joh...